Réf. int :170706A5020 Mme BEZIER Valerie NJF : 15 STREAT BALAN 29810 PLOUARZEL Né(e) le : 09/05/1977 Réf. ext : 170086511 Age : 45 ans Prescripteur : Docteur FAVIE Alain 170706A5020 Docteur FAVIE Alain POLYCLINIQUE KERAUDREN RUE ERNESTINE DE TREMAUDAN BP 72044 29220 BREST CEDEX 2
1 - SKIN EXAMINATION: CONTROL SKIN (UNTREATED)
1 - SKIN EXAMINATION: CONTROL SKIN (UNTREATED)
Macroscopic examination
Formalin fixation time: until 6/7 20h
Size: 3.5 x 2 x 1.2 cm
Skin flap: 2 x 2.5 cm
Inclusion: sample in 1 block
Microscopic examination
The epidermis is of normal thickness. It appears slightly scalloped with no signs of disorganisation.
The basement membrane contains rare apoptotic cells without atypia.
The underlying dermis has a discrete lesion of non-specific capillaritis without vasculitis.
It contains rare pilosebaceous appendages without abnormality.
The collagen fibres appear here of variable thickness, rather short but not fragmented without elastosis.
The hypodermis is discreetly congestive. - Orcein staining shows the presence of fairly rare medium-sized elastic fibres. - Trichrome staining shows clusters of collagenous fibres, often short and fragmented of homogeneous appearance, not dissociated.
2 - CUTANEOUS EXCISION: SKIN TREATED WITH NEOCARE ELITE BY BLOOMEA
Clinical information
Skin adjacent to the control skin.
3 sessions spaced 7 to 10 days apart.
Macroscopic examination
Size: 3.2 x 1.5 x 1.1 cm
Skin flap: 2.3 x 1.8 cm
Inclusion: 2 blocks
Microscopic examination
The epidermis is architecturally preserved with no visible keratinocyte alteration.
The stratum corneum does not appear modified.
The underlying dermis contains discrete lesions of chronic, unenhanced capillaritis. - Staining with orcein shows a slight hyperplasia of the elastotic network, estimated at 15 to 20%, depending on the area, without dissociation or reactive inflammation. - Trichrome staining shows a discrete condensation of collagen fibres whose arrangement and architecture do not appear to be altered.
Conclusie
The effects of NEOCARE ELITE on the sample examined include an increase in the number of elastin fibers estimated at 15 to 20%, associated with a slight densification of collagen fibers.
Op 24/09/2021
Dr Anabelle WERBROUCK-CHIRAUX